Asacol HD (mesalamine) delayed-release tablets are generally well tolerated. In studies of flare-ups, some people taking Asacol HD reported:

  • Headache
  • Upset stomach
  • Sore throat
  • Stomach pain
  • Worsening of UC symptoms

While these are the most common side effects, serious side effects may occur with Asacol HD. Talk with your doctor if you have questions about the potential Asacol HD side effects. It ís also important to visit your doctor periodically to monitor your condition and discuss your treatment plan.